Script

The magic part here is the "Host" HTTP header which is sent by the browser, and will route to the correct application.

  #!/usr/bin/perl
  use Toadfarm -init;
  mount "/home/www/project1/script/app1" => {
    Host => "example.com",
  };
  mount "/home/www/project2/script/app2" => {
    Host => "your-other-domain.com",
  };
  start ["http://*:8080"], workers => 8;

Note: Defining a default app might be an idea, in case the a browser doesn't set the "Host" header.